NCT06662812已完成不适用
Disease Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery (GRNDaD) Registry
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Novartis
- 入组人数
- 1,665
- 试验地点
- 1
- 主要终点
- Number of Patients in the Globin Research Network for Data and Discovery (GRNDaD) Registry who Received a Disease Modifying Therapy (DMT)
研究概览
简要总结
This was a retrospective observational cohort study. This study was a secondary analysis of individuals with sickle cell disease (SCD) enrolled in the GRNDaD registry.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Number of Patients in the Globin Research Network for Data and Discovery (GRNDaD) Registry who Received a Disease Modifying Therapy (DMT)
时间窗: Up to 2 years
DMTs included: hydroxyurea, voxelotor, crizanlizumab, l-glutamine, and chronic red cell transfusion.
次要结局
- Number of Patients in the Globin Research Network for Data and Discovery (GRNDaD) Registry Using Hydroxyurea Categorized by Gender(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Hydroxyurea Categorized by Genotype(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Hydroxyurea Categorized by Age(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Voxelotor Categorized by Gender(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Voxelotor Categorized by Genotype(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Voxelotor Categorized by Age(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Crizanlizumab Categorized by Gender(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Crizanlizumab Categorized by Genotype(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Crizanlizumab Categorized by Age(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using L-glutamine Categorized by Gender(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using L-glutamine Categorized by Genotype(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using L-glutamine Categorized by Age(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Chronic Transfusion Categorized by Gender(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Chronic Transfusion Categorized by Genotype(Up to 2 years)
- Number of Patients in the GRNDaD Registry Using Chronic Transfusion Categorized by Age(Up to 2 years)
- Number of Hospital Admissions Categorized by Age(Up to 2 years)
- Mean Number of Hospital Admissions(Up to 2 years)
- Number of Emergency Department Visits Categorized by Age(Up to 2 years)
- Mean Number of Emergency Department Visits(Up to 2 years)
研究者
研究点 (1)
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