Study of the Effect of the Auditory Stimulation on Stuttering Symptoms in Patients With a Deficit of Spectral Power in the EEG Beta Frequency Band
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Speech disfluencies
研究概览
简要总结
In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes.
详细描述
Stuttering is a speech disorder that affects more than 70 million people worldwide, limiting their ability to communicate and socialize. During recent decades, several studies have demonstrated a link between stuttering and a deficit of β EEG spectral power.
In this study, the investigators will research the efficacy of a novel auditory neuro modulating technology that leverages euphonic music tracks with broad-spectrum binaural beats to induce selective EEG spectral power changes. Participants are adults with stuttering and without speech disfluencies from the control group will expose to euphonic binaural stimuli for 5 minutes. The brain electrical activity patterns (EEG) and ECG bio-signals will record prior to, during, and after exposure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults with stuttering (stammering) symptoms;
排除标准
- •Hearing disabilities;
- •Applying other drugs or devices simultaneously;
结局指标
主要结局
Speech disfluencies
时间窗: The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation
The total number of repetitions, blocks and prolongations during the speech (assessed by speech therapist) measured before, just after and 10 minutes after auditory stimulation
次要结局
- Heart Rate Variability Stress Index [a.u.](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
- Heart Rate Variability meanRR [ms](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
- Heart Rate Variability Total Power [ms^2](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
- Heart Rate Variability SDNN [ms](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
- Heart Rate Variability RMSSD [ms](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
- EEG spectral power in beta frequency range, [uV^2](The outcome measure will be assessed between 5-minute intervals before stimulation, just after and 10 minutes after stimulation)
研究者
Dmytro Chernetchenko
PhD, Associate Professor
Oles Honchar Dnipro National University