Relationship Between Lactate and Venous Oxygen Saturation Gradient of Carbon Dioxide in Patients With Post Cardio Respiratory Syndrome
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- mortality
研究概览
简要总结
There is a correlation between hospital mortality and changes in markers of tissue perfusion, lactate, and venous oxygen saturation and carbon dioxide gradient.
详细描述
Evaluation of the serum carbon dioxide gradient (GapCO2), central venous saturation (ScvO2) and the clearance of serum lactate (Clac) in predicting hospital mortality after cardiac arrest syndrome (post-PCR).
Prospective study, unicenter - Intensive Care Unit - HNSC. Period: May/2010 to June/2011. Serial assessment of GapCO2 of ScvO2 Clac and the first 72 hours post-PCR. Excluded under 18, survival of less than 6HS, pregnant women, traumatized, post-operative hypothermia and liver disease. T-student test, 95% (p <0.05).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients hospitalized in the intensive care unit after cardiopulmonary arrest with any pace
排除标准
- •pregnant women, traumatized, post-operative(less 7 days), hypothermia and liver disease.
- •patients hospitalized in the intensive care unit with more than 6 hours post cardiac arrest
- •less 18 years old
结局指标
主要结局
mortality
时间窗: 1 year
次要结局
- correlation of clearance markers of perfusion with the use of vasopressor and positive fluid balance(6 hours)
研究者
Vanessa Martins de oliveira
Principal Investigator
Hospital Nossa Senhora da Conceicao