The Effect of Chocolate on Vascular Function of Endurance Runners
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- 5km Time
研究概览
简要总结
The aim of this study is to examine the effects of chocolate on the vascular function of endurance runners through a crossover study involving male runners consuming both dark and white chocolate.
详细描述
Participants will be male endurance runners who will receive both black and white chocolate interventions. Arterial stiffness, cardiovascular parameters, respiratory parameters, and running performance will be assessed before and after each intervention period. The study will involve a two-week intervention period for each type of chocolate, with a washout period in between. The primary outcome measure will be arterial stiffness, while secondary outcome measures will include cardiovascular and respiratory parameters, as well as running performance. The study is expected to provide insights into the effects of chocolate consumption on vascular function in endurance athletes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- None
盲法说明
Τhe study does not use the method of blind evaluation due to the nature of the interventions, which are easily identifiable by the participants
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Gender: Male
- •Age: 25-55 years
- •Healthy status
- •Active endurance runner
- •Regular physical activity (at least 3 times per week)
- •Availability on specific days and times for research sessions
- •Willingness and consistency
排除标准
- •Allergies or Intolerances: Participants with known allergies or intolerances to chocolate or any of its ingredients.
- •Cardiovascular Diseases: Participants with known cardiovascular diseases or history of cardiac episodes.
- •Metabolic Disorders: Individuals with diabetes or other metabolic disorders that may affect glucose and insulin metabolism.
- •Contradictory Diet: Individuals following specific diets that may affect the study, such as high or low flavonoid diets.
- •Medication Use: Individuals taking medications that affect vascular function, such as antihypertensives or anticoagulants.
- •Smoking: Smokers or individuals who have quit smoking within the last six months.
- •Substance Abuse: Individuals with a history of alcohol or substance abuse.
- •Patients with Chronic Diseases: Individuals with serious chronic diseases that may affect the study outcomes.
- •Participation in Other Studies: Individuals participating in other clinical trials or research that may affect the study outcomes.
- •Physical Condition: Individuals who are not regular runners or who do not exercise regularly at a level similar to other participants.
研究组 & 干预措施
A Chocolate Arm
Intervention period 1:The group will consume 50 grams of dark chocolate daily for two weeks.
Washout period: Two-weeks
Intervention period 2: The group will consume 40 grams of white chocolate daily for two weeks.
干预措施: Dark chocolate Intervention (Other)
A Chocolate Arm
Intervention period 1:The group will consume 50 grams of dark chocolate daily for two weeks.
Washout period: Two-weeks
Intervention period 2: The group will consume 40 grams of white chocolate daily for two weeks.
干预措施: White chocolate Intervention (Other)
B Chocolate Arm
Intervention period 1:The group will consume 40 grams of white chocolate daily for two weeks.
Washout period: Two-weeks
Intervention period 2: The group will consume 50 grams of dark chocolate daily for two weeks
干预措施: Dark chocolate Intervention (Other)
B Chocolate Arm
Intervention period 1:The group will consume 40 grams of white chocolate daily for two weeks.
Washout period: Two-weeks
Intervention period 2: The group will consume 50 grams of dark chocolate daily for two weeks
干预措施: White chocolate Intervention (Other)
结局指标
主要结局
5km Time
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Total time taken to complete a 5-kilometer run, measured in minutes and seconds.
AIx (Augmentation Index)
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Measurement of arterial stiffness, calculated as the difference between the first and second systolic peaks of the arterial waveform, expressed as a percentage (%)
Exercise Time in Cardiopulmonary Exercise Testing
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Total duration of exercise during cardiopulmonary exercise testing, measured in minutes.
5km Speed
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Average speed during a 5-kilometer run, expressed in kilometers per hour (km/h).
CF-PWV (Carotid-Femoral Pulse Wave Velocity)
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Measurement of the velocity of the pressure wave between the carotid and femoral arteries, expressed in meters per second (m/s)
VO2max (Maximal Oxygen Uptake)
时间窗: Baseline and at the end of each 2-week intervention period (after consumption of dark chocolate and after consumption of white chocolate).
Maximum amount of oxygen consumed per minute during incremental exercise, expressed in milliliters per kilogram per minute (mL/kg/min)
次要结局
未报告次要终点
研究者
Evangelia Kouidi
Professor, Director of the Laboratory of Sports Medicine
Aristotle University Of Thessaloniki