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临床试验/NL-OMON41031
NL-OMON41031尚未招募不适用

respiratory muscle activity during mechanical ventilation and spontaneous breathing trials - respiratory muscles during mechanical ventilation

Erasmus MC, Universitair Medisch Centrum Rotterdam0 个研究点目标入组 20 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • age >18 yr.
  • respiratory failure due to severe weakness of the respiratory muscles in absence of pulmonary disease (e.g. myasthenia, cervical spine injury)
  • respiratory failue de to severe weakness of the respiratory muscles with concomitant lung pathology (e.g. end stage ARDS, COPD and lung transplant)
  • ability to breathe spontaneously for 10 minutes
  • written informed consent

排除标准

  • Reduced respiratory drive and inability to breath spontaneously without ventilator support for > 10 minutes
  • Hemodynamic instability defined as blood pressure below 100 / 60 mmHg
  • Air leaks by cannula or chest tubes: defined as leaks above 1 liter per minute
  • Severe hypoxemia defined as paO2 below 8 kPa
  • Esophagus or neck surgery

研究者

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