The Consistency of Cardiac Output Measured by Electrical Cardiometry and Pulmonary Artery Catheter in Cardiac Surgery Patients With Pulmonary Arterial Hypertension or Right Heart Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 199
- 试验地点
- 1
- 主要终点
- cardiac output by pulmonary artery catheter
研究概览
简要总结
Currently, the gold standard method to estimate CO in patients with PAH or RV dysfunction is pulmonary artery catheter (PAC), however, the invasiveness and complexity of PAC has limited its usefulness in many clinical scenarios. By measuring the thoracic electrical bioimpedance, electrical cardiometry (EC) technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, in patients with pulmonary arterial hypertension (PAH) and/or right ventricular (RV) dysfunction, few study has been reported. The aim of this study is to evaluate the agreement between CO measured by PAC as the referenced method and CO measured by EC technique in patients with PAH and/or RV dysfunction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult cardiac surgery patients
- •pulmonary artery hypertension and/or right heart dysfunction
- •mechanical ventilation
排除标准
- •life threatening arrhythmia
- •severe valve regurgitation
- •left ventricular ejection fraction less than 30%
- •patients with mechanical circulatory support
研究组 & 干预措施
patients with pulmonary artery hypertension and/or right ventricular dysfunction
干预措施: passive leg raising (Behavioral)
patients with pulmonary artery hypertension and/or right ventricular dysfunction
干预措施: dobutamine test (Drug)
patients with pulmonary artery hypertension and/or right ventricular dysfunction
干预措施: inhaled nitric oxide (Drug)
结局指标
主要结局
cardiac output by pulmonary artery catheter
时间窗: 30 minutes after nitric oxide inhalation
measuring cardiac output using pulmonary artery catheter
cardiac output by electrical cardiometry
时间窗: 30 minutes after nitric oxide inhalation
measuring cardiac output using electrical cardiometry
次要结局
未报告次要终点
