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临床试验/NCT05817487
NCT05817487已完成不适用

Effects of Crossover Point Exercise and High-intensity Interval Training on Vascular Health in Young Overweight Females

Beijing Sport University1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2019年2月18日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
1
主要终点
brachial-ankle pulse wave velocity (baPWV)

研究概览

简要总结

The goal of this study is to determine the effects of high-intensity interval training and crossover point exercise training on vascular health in young overweight women.

详细描述

In recent years, improving cardiovascular health through exercise has become a popular research question, however, it is not clear which intensity and modes of exercise bring more benefits. Crossover point(COP) intensity has great medical potential as a personalized exercise intensity that is based on substrate utilization mode, especially in overweight and obese people.On the other hand, several studies have demonstrated that HIIT is an effective method in improving vascular endothelial dysfunction. During our study, we evaluated the vascular health changes in young overweight women who received either COP exercise or HIIT exercise for 10 weeks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Female, 18-30 years old
  • •Body mass index (BMI) < 28 kg/m2 and ≥ 24 kg/m2
  • •No exercise habit, and no recent new exercise plan
  • •No contraindications to exercise

排除标准

  • •Participates had an orthopedic or other condition that limited participation in daily exercise
  • •Participates had a history of myocardial infarction, stroke, diabetes mellitus, chronic respiratory disease or cancer
  • •Participates had smoking or alcohol behavior

研究组 & 干预措施

HIIT group

Experimental

干预措施: high-intensity interval training (HIIT) (Behavioral)

COP group

Experimental

干预措施: crossover point(COP) exercise training (Behavioral)

结局指标

主要结局

brachial-ankle pulse wave velocity (baPWV)

时间窗: 10 weeks

The change of baPWV before and after intervention

blood pressure

时间窗: 10 weeks

The change of blood pressure before and after intervention

次要结局

  • Interleukin 6 (IL-6)(10 weeks)
  • Homocysteine (HCY)(10 weeks)

研究者

发起方
Beijing Sport University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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