Does Milk Augment the Acute Effect of Exercise on Bone Turnover and Inflammation
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 13
- 试验地点
- 2
- 主要终点
- Acute Bone Cell Activity
研究概览
简要总结
This study analyzes whether dairy supplementation positively impacts loading exercise-induced bone cell activity and inflammation in healthy young females.
详细描述
Introduction: Two million individuals at a cost of around 2.3 billion dollars a year in Canada suffer from osteoporosis. Research that emphasizes the treatment of this disease is important, but so is research that focuses on prevention; reducing bone loss and/or increasing bone mass when young. In addition, inflammation is an issue as it strongly relates to chronic disease. Countermeasures to improve bone health and inflammation, such as nutrition and exercise, should be explored and implemented. The proposed research combines both nutrition and exercise along with the assessment of bone turnover markers and inflammation in healthy young females, and aims to determine whether dairy versus a carbohydrate-based beverage positively impacts acute bone turnover and the inflammatory response following a bout of resistance and plyometric exercise.
Design: Randomized controlled crossover trial.
Participants: 13 healthy university aged females.
Methods: Participants were asked to complete 2 different acute exercise and nutritional supplement trials. Each trial will be assigned in random order. The two trials were: 1) exercise+carbohydrate (CHO), and 2) exercise+milk (Milk). The whole study, per participant, took a maximum of 8-12 weeks to complete as each supplement trial was separated by ~4 weeks. Each treatment is outlined below.
******DUE TO COVID-19, we removed the treatment trial which involved milk+creatine supplementation. Despite randomization, and before the trial was closed, only 11 participants completed this trial********
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
Those completing the analyses were masked to the treatments.
入排标准
- 年龄范围
- 18 Years 至 30 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Female between the ages of 18 and 30 years
- •Normal BMI (18.5-24.9) kg/m2
- •Low to moderately physically active (0-2 times/week)
- •No allergy to dairy protein or lactose intolerance
- •On no medication related to a chronic condition
- •On birth control (or not but with regular mensural cycle)
排除标准
- 未提供
结局指标
主要结局
Acute Bone Cell Activity
时间窗: 48 hours post exercise
Bone markers (OPG, RANKL, OC) measured in serum/plasma.
次要结局
未报告次要终点
研究者
Andrea Josse
Assistant Professor
York University
