跳至主要内容
临床试验/NCT01992484
NCT01992484Unknown不适用

Association Between the Antiplatelet Drug Efficacy/Safety and Platelet Function in Patients Treated With Novel Platelet Inhibitors Due to an Acute Coronary Syndrome

Medical University of Vienna1 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2012年8月最近更新:
适应症

试验速览

阶段
不适用
入组人数
1,000
试验地点
1
主要终点
Net clinical benefit.

研究概览

简要总结

The aims of the study are to:

  • explore whether platelet reactivity in patients treated wih novel platelet inhibitors is associated with clinical outcome
  • investigate whether a therapeutic window exist for novel platelet inhibitors
  • investigate the incidence of adverse events under treatment with novel platelet inhibitors in the real life clinical scenario
  • investigate the association between genetic polymorphisms, inflammation, platelet reactivity and clinical outcome
  • investigate synergistic effects between aspirin and novel platelet inhibitors

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Signed informed consent
  • Acute coronary syndrome at admission
  • Planned treatment with novel platelet inhibitors

排除标准

  • * Participation in interventional trials

结局指标

主要结局

Net clinical benefit.

时间窗: 1 year

A composite of MACE and BARC=\>2 bleedings.

次要结局

  • MACE and Major bleeding(1 year)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jolanta Siller-Matula

PD Dr.med. PhD

Medical University of Vienna

研究点 (1)

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