NCT01992484Unknown不适用
Association Between the Antiplatelet Drug Efficacy/Safety and Platelet Function in Patients Treated With Novel Platelet Inhibitors Due to an Acute Coronary Syndrome
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Net clinical benefit.
研究概览
简要总结
The aims of the study are to:
- explore whether platelet reactivity in patients treated wih novel platelet inhibitors is associated with clinical outcome
- investigate whether a therapeutic window exist for novel platelet inhibitors
- investigate the incidence of adverse events under treatment with novel platelet inhibitors in the real life clinical scenario
- investigate the association between genetic polymorphisms, inflammation, platelet reactivity and clinical outcome
- investigate synergistic effects between aspirin and novel platelet inhibitors
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Signed informed consent
- •Acute coronary syndrome at admission
- •Planned treatment with novel platelet inhibitors
排除标准
- •* Participation in interventional trials
结局指标
主要结局
Net clinical benefit.
时间窗: 1 year
A composite of MACE and BARC=\>2 bleedings.
次要结局
- MACE and Major bleeding(1 year)
研究者
Jolanta Siller-Matula
PD Dr.med. PhD
Medical University of Vienna
研究点 (1)
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