IRCT201112146948N2已完成未知
Comparison of the adverse effects of intravenous N-acetylcysteine with intravenous and oral N-acetylcystein in acetaminophen toxicity
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit(—)
- 性别
- All
入选标准
- •The inclusion criteria: Patients with acetaminophen poisoning; ingesting the toxic acetaminophen dose (=7.5g); aged = 18 years old; coming to the hospital before 8 hours after acetaminophen ingestion.
- •The exclusion criteria: Less than 7.5g acetaminophen ingesting; aged under 18 years old; coming to the hospital after 8 hours after acetaminophen ingestion; vomiting two times after oral NAC was given; pregnant patients; those who had risk factors for hepatic toxicity (e.g. those who had hepatic cirrhosis; chronic ethanol ingestion; usage of substances that induce cytochrome P450 enzyme activity including rifampin; phenobarbital; isoniazid; phenytoin and carbamazepine).
排除标准
- 未提供
研究者
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