NCT03348384已完成早期 1 期
Linking Nociceptive Opioid Peptide (NOP) Receptors With Relapse in Cocaine Use Disorders
适应症
干预措施
相关药物
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 入组人数
- 49
- 试验地点
- 1
- 主要终点
- [C-11]NOP-1A VT
研究概览
简要总结
The goal of this study is to compared [C-11]NOP-1A binding in recently abstinent cocaine use disorders and controls.
详细描述
This will allow for understanding brain stress and anti-stress mechanisms that underlie abuse of cocaine in humans.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Cocaine use disorders
Experimental
PET scan
干预措施: [C-11] (Radiation)
Cocaine use disorders
Experimental
PET scan
干预措施: NOP-1A (Drug)
Controls
Experimental
PET scan
干预措施: [C-11] (Radiation)
Controls
Experimental
PET scan
干预措施: NOP-1A (Drug)
结局指标
主要结局
[C-11]NOP-1A VT
时间窗: Baseline
VT-volume of distribution expressed relative to total plasma
次要结局
未报告次要终点
研究者
Rajesh Narendran
Visiting Professor in Radiology
University of Pittsburgh
研究点 (1)
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