跳至主要内容
临床试验/NCT05374460
NCT05374460已完成不适用

Factors Affecting Sensory and Motor Learning

Indiana University3 个研究点 分布在 1 个国家目标入组 389 人开始时间: 2022年4月29日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
389
试验地点
3
主要终点
Realignment

研究概览

简要总结

How participants perceive the position of their own hand in various contexts will be examined. This will include changing the visual display to suggest the hand is in a slightly different position, and asking participants to indicate where they think it is by pointing with their other hand.

详细描述

Hand position can be estimated visually, from an image on the retina, and proprioceptively, from sensors in the joints, muscles, and skin. The brain is thought to weight and combine available sensory estimates to form an integrated multisensory estimate. Inherent in this process is the capacity to realign one or both sensory estimates when they become spatially mismatched, as when washing dishes with the hands immersed in water, which refracts light. It is generally assumed that if a person knows about the sensory mismatch somehow, the realignment will not occur. This assumption will be tested in two experiments by giving people this information in different ways. Expt. A: Conscious awareness of the mismatch will be presented in different ways, or absent. Expt. B: Movement error feedback will be presented in different ways, or absent.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Between the ages of 18-45 years old
  • Right-handed.
  • Covid has been found to have neurological effects in some people, but mostly the effects on sensorimotor control and neurophysiology are unknown. So we will only include individuals who report being free of Covid symptoms in week preceding testing.

排除标准

  • Past or present history of seizure, stroke, any brain or peripheral nerve disease, severe head trauma, or spinal cord surgery.
  • Learning or attention conditions such as ADHD.
  • Orthopedic or pain conditions, or a history of seriously injured bones, joints or muscles in either arm.
  • Lack of normal or corrected-to-normal vision.

研究组 & 干预措施

Conscious awareness: No information

Sham Comparator

Told nothing about the visuo-proprioceptive mismatch. Hand remains hidden beneath mirror that shows visual display. (control)

干预措施: Attend to the targets (Behavioral)

Conscious awareness: Explanatory diagram

Experimental

Told in advance about the visuo-proprioceptive mismatch, which will be explained with a diagram. Hand remains hidden.

干预措施: Explanatory diagram (Behavioral)

Conscious awareness: Direct vision of hand

Experimental

Foamboard under mirror removed, making the mirror see-through and the hand directly visible.

干预措施: Direct vision (Behavioral)

Movement feedback: Target hand

Experimental

Movement feedback about the target hand.

干预措施: Movement feedback, target hand (Behavioral)

Movement feedback: Pointing hand

Experimental

Movement feedback about the pointing hand.

干预措施: Movement feedback, pointing hand (Behavioral)

Movement feedback: No feedback

Sham Comparator

No movement feedback (control)

干预措施: No movement feedback (Behavioral)

结局指标

主要结局

Realignment

时间窗: 1 day

Measured by comparing where the subject points on a touchscreen when indicating perceived position of visual and proprioceptive targets early vs. late in the behavioral task.

次要结局

  • Visuo-proprioceptive weighting(1 day)
  • Target estimation variance(1 day.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

David Koceja

Professor

Indiana University

研究点 (3)

Loading locations...

相似试验