Identification of Genetic, Biochemical and Hormonal Factors Contributing to Atrial Fibrillation
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 1,300
- 试验地点
- 2
- 主要终点
- Genetic variants associated with atrial fibrillation
研究概览
简要总结
The purpose of this study is to establish a genebank repository of blood samples and data to generate information about the hereditary (genetic) basis of atrial fibrillation.
详细描述
Blood samples and data will be collected from subjects with atrial fibrillation and normal controls. The primary aim of future research using these samples is to identify mechanisms and pathogenesis of atrial fibrillation. Through this information, we hope to identify targets for new therapies and improve knowledge and understanding of atrial fibrillation. Identification of disease genes could improve strategies that prevent progression of atrial fibrillation to more persistent disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •for Atrial Fibrillation group:
- •Male or female at least 18 years old
- •Subjects with a history of or current Atrial Fibrillation
- •Subjects able to give informed consent
排除标准
- •for Atrial Fibrillation group: no history of atrial fibrillation
- •Inclusion Criteria for Controls:
- •Male or female at least 18 years old
- •Subjects with no history of Atrial Fibrillation
- •Subjects able to give informed consent Exclusion Criteria for controls: History of atrial fibrillation
研究组 & 干预措施
atrial fibrillation
Atrial fibrillation
Control
Control subjects with no atrial fibrillation
结局指标
主要结局
Genetic variants associated with atrial fibrillation
时间窗: Baseline
Genome-wide association study of atrial fibrillation
次要结局
未报告次要终点
研究者
Mina Chung, MD
Principal Investigator
The Cleveland Clinic