Serology Screening Test for the Detection of Nasopharyngeal Carcinoma in Zhongshan City
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- The early detection rate (stage I and II) of Nasopharyngeal Carcinoma
研究概览
简要总结
The primary objective is to determine the early diagnosis rate and mortality rate of the Nasopharyngeal Carcinoma (NPC) in the study population.
The secondary objective is to determine the incidence of NPC in the study population.
详细描述
The research is to evaluate the effect of NPC screening, also as an extended study of Screening for Nasopharyngeal Carcinoma in High Risk Populations (NCT00941538).
The program was conducted in Xiaolan and Minzhong towns of Zhongshan city in 2012.
All participants will be tested for anti-EBV antibody by using serum samples. Participants are stratified into those having high, moderate and low antibody levels, those having moderate antibody levels are invited to retest annually in the following 3 years and those found to have high antibody levels on these occasions are referred to centers for diagnostic workup for NPC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 59 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Subject residents in Zhongshan city
- •Subject is 30 to 59 years of age inclusive
- •Subject has no medical record of nasopharyngeal carcinoma
- •Subject has psychical condition and well consciousness
- •Subject is able to comprehend, sign, and date the written informed consent document to participate in the study.
排除标准
- •Subject has heavy cardiovascular, liver or kidney disease
- •Subject has medical record of nasopharyngeal carcinoma
- •Subject who is not residing in Zhongshan City
结局指标
主要结局
The early detection rate (stage I and II) of Nasopharyngeal Carcinoma
时间窗: 10 years
The mortality rate of Nasopharyngeal Carcinoma
时间窗: 10 years
次要结局
- The incidence of Nasopharyngeal Carcinoma(10 years)
研究者
Mingfang Ji
Principal Investigator
Zhongshan People's Hospital, Guangdong, China