Effects of Hypothermia on Delayed Neurocognitive Recovery: an Observational Trial Among Patients Undergoing Cardiac-Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 168
- 试验地点
- 1
- 主要终点
- Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery
研究概览
简要总结
Post-operative cognitive dysfunction is a common disease in patient undergoing general anaesthesia, especially in older patients. No correlations have been yet studied between intraoperative hypothermia and incidence of Delayed Neurocognitive Recovery. Investigators are going to estimate the Relative Risk of Hypothermia and emergence of Post-operative cognitive dysfunction in cardiac-surgery patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults patients undergoing Cardiac - Surgery intervention with extracorporeal circulation
排除标准
- •Neurological disease before surgery
- •Sedation in Cardiac-Surgery Intensive Unit > 6 hours
- •Cerebral regional Oxygen saturation <20% baseline during surgery
结局指标
主要结局
Incidence of Delayed Neurocognitive Recovery in Cardiac-Surgery
时间窗: Patients will be subjected to Frontal Assessment Battery test one day before surgery and 4-6 days after surgery
Discover changes between pre-operative Frontal Assessment Battery test score and post-operative Frontal Assessment Battery test score and
次要结局
- Effects of hypothermia during Extracorporeal Circulation in Cardiac Surgery(One day before surgery and 4-6 days after surgery patients will be subjected to cognitive test to diagnosticate Post-Operative Cognitive Decline)
研究者
Federico Linassi
MD, Principal Investigator
University of Padova