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临床试验/NCT07684495
NCT07684495尚未招募不适用

Aerobic Exercises Versus Sub Occipital Myofascial Release on Memory Function in Females With Premenstrual Syndrome.

Cairo University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年7月3日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
40
试验地点
1
主要终点
Memory function

研究概览

简要总结

This study will be conducted to investigate the effect of aerobic exercises versus sub occipital Myofascial release on memory functions in females with premenstrual syndrome.

详细描述

The pooled prevalence of reproductive age women affected with premenstrual syndrome (PMS) worldwide amounts to 47.8%. Among these, about 20% of women experience symptoms severe enough to disrupt their daily activities, and the remaining have mild to moderate symptoms. They can experience an exacerbation of insomnia, memory problems, difficulty maintaining focus, and fatigue in the both follicular phase and luteal phase, but more noticed during the luteal phase. Memory deficit could affect those women social activities and one's daily positive functioning. Therefore, some females and their providers seek alternative treatments such as Aerobic exercise which represents a cost-effective, widely available, natural, and self-administered treatment with no adverse side effects, and it is reported that Aerobic exercise resulted in 16.5% increase in hippocampal volume and 53.7% increase in memory, as well as increased hippocampal resting-state functional connectivity.

And also, it is found the noticed role of suboccipital muscles release in improving memory functions through enhancing cerebral blood flow to the brain via vertebral artery, and also regulation of cortisol level that interferes with memory and stress.

Till now, there is no previous study illustrating the difference between the effect of aerobic exercise and sub occipital muscle release on memory functions in females with PMS. So, this study will be the first one in this issue. Therefore, it will have valuable benefits in physical therapy field and scientific research.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Females with premenstrual syndrome and memory function deficits have to meet the following criteria in order to participate in this study:
  • Their age ranged from 18 to 30 years old.
  • Their body mass index (BMI) ranged from 18.5 - 30 kg/cm2.

排除标准

  • Any medications that can affect central nervous system or memory function.
  • Any neurological disorders affect their memory function.
  • Pregnant women.
  • Daily smokers.
  • Had a concussion or head trauma within the past 30 days.
  • Took any illegal drugs or alcohol within the past 30 days.

结局指标

主要结局

Memory function

时间窗: 6 weeks

Assessment of memory function will be done by the free recall test. The word list will contain 10 words selected randomly. These words would be administered to the patient one by one with interval time 1 second between each word with total words presentation time 10 seconds. The presentation of these words will be though a digital screen using a designed video showing these words arranged in order with a fixed interval 1 second between each word. The patient will be instructed immediately to recall these words verbally at any order. The total score is 10 and one point will be accounted for each word will be recalled correctly

Prospective and retrospective memory questionnaire (PRMQ)

时间窗: 6 weeks

It will be used to assess memory functions. The measure consists of 16 individual items. The Structure of the PRMQ consists of 16 Items total , each item is rated on a 5-point scale (1 = Never , 2 = Rarely , 3 = Sometimes , 4 = Often , 5 = Very Often). These 16 items, evenly divided into 8 prospective memory items and 8 retrospective memory items. Each item describes a common memory lapse, giving a high score to an item means a high memory deficits at that item. The total score ranges from 16 to 80, with higher scores indicating a greater frequency of memory lapse and deficit.

次要结局

  • Perceived Stress Scale (PSS)(6 weeks)
  • Cervical pain intensity(6 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Gehad Mohamed Ali Ahmed

Principal investigator

Cairo University

研究点 (1)

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