The Consistency of Cardiac Output Measured by Pulmonary Artery Catheter and LiDCO in Cardiac Surgical Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Cardiac Output measurement after PLR
研究概览
简要总结
- To evaluate the consistency of cardiac output measured by pulmonary artery catheter and LiDCO in cardiac surgical patients
- To evaluate whether different hemodynamic monitoring methods can accurately detect the trend of cardiac output changes
详细描述
Close monitoring of cardiac output (CO), especially in patients before and after intervention(such as volume expansion, diuresis, vasoconstriction, vasodilation therapy), could help to adjust the treatment strategy in cardiac surgical patients. Pulmonary artery catherization (PAC) has been used for hemodynamic monitoring for more than four decades. In spite of its invasiveness, it remains the clinical reference method for the assessment of CO at the bedside. Nowadays, many less invasive alternatives, such as LiDCO Rapid Pulse Contour Analysis System (LiDCO Ltd., Cambridge, United Kingdom), are already available on market. However, consistency between different hemodynamic monitoring results still raise concern. And whether hemodynamic monitoring could accurately detect the changes of these parameters before and after intervention is an important issue in clinical practice. In this study, the investigators are going to collect CO and changes of CO from PAC and LiDCO before and after intervention (passive leg raising and dobutamine stress test) in cardiac surgical patients. Our resulst could provide important reference for cardiac surgical patients how to choose appropriate hemodynamic monitoring tools and how to interpret the results of hemodynamic monitoring.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •cardiac surgery
- •hemodynamic monitoring (PAC, LiDCO)
- •mechanical ventilation
排除标准
- •cardiac arrhythmia
- •moderate to severe aortic, mitral and tricuspid regurgitation
结局指标
主要结局
Cardiac Output measurement after PLR
时间窗: 1 minute after PLR
Cardiac Output measured after PLR
Baseline Cardiac Output measurement
时间窗: within1 minute at baseline position
Cardiac Output measured at baseline position (horizontal position)
Cardiac Output measurement after Dobutamine stress test
时间窗: 5 minutes after dobutamine stress test
Cardiac Output measured after dobutamine stress test
次要结局
未报告次要终点
