Splint with Ozone Injection for Mild and Moderate Carpal Tunnel: an Electrodiagnostic Study
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 34
- 试验地点
- 1
- 主要终点
- Boston Carpal Tunnel Syndrome Questionnaire
研究概览
简要总结
This study will investigate the effectiveness of repeated ozone therapy combined with splint therapy for carpal tunnel syndrome (CTS).CTS patients will be split into two groups: ozone plus splint and splint only. Both groups will use wrist splints for 3 weeks, with the ozone+splint group receiving weekly ozone injections for three weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •being 18-65 years, with mil-modarete CTS, symptoms continued for at least 3 months
排除标准
- •hand edema or prior injections, thenar atrophy, prior CTS surgery, severe EMG results, recent physical therapy, steroids, or platelet-rich plasma for CTS in the past year, and conditions causing secondary CTS (e.g., thyroid disorders, diabetes, pregnancy, rheumatoid arthritis, Dupuytren's contracture, inflammatory arthritis, connective tissue diseases). Also excluded: neck or arm pain conditions (e.g., cervical disc herniation, wrist fracture, proximal upper extremity entrapment neuropathy, polyneuropathy, peripheral nerve damage, fibromyalgia), history of G6PD deficiency, uncontrolled hyperthyroidism, thrombocytopenia, and contraindications to general ozone therapy (e.g., ACE inhibitors for severe cardiovascular instability).
结局指标
主要结局
Boston Carpal Tunnel Syndrome Questionnaire
时间窗: 10 minutes
As the score obtained from the survey increases, the improvement increases.
visual analog scale
时间窗: 1 minute
As the score approaches 10, the intensity of pain felt increases.
electromyography (EMG)
时间窗: 10 minutes
In the electrophysiological examination, median sensory nerve conduction studies and median motor nerve conduction studies will be measured. Median motor nerve latency, median motor nerve conduction velocity, and compound muscle action potential amplitude will be measured and recorded.
次要结局
未报告次要终点
研究者
Emine Cihan
Assist. Prof. Dr.
Selcuk University