Observational study to compare the effect of altitude on cardiopulmonary reserves of different individuals staying more than 06 weeks at 10,000 ft and 15,000ft respectively
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Compare the opening SpO2 and then SpO2, HR before and after 6 minute walk test
研究概览
简要总结
Individuals posted at high altitudes are in continous state of hypoxemia. Newly inducted individuals,despite getting acclimatized and working at these altitudes for more than 6 weeks, continue to have fatigue and breathlessness on exertion while doing daily routine chores . With sudden surge in the population at high altitude and with sudden surge of illness, accidents and effects of war like situations it is necessary to determine the effect in change in altitude with the help of surrogate markers like SpO2, 6 minute walk test limited to Heart Rate only and Breath holding Time.
This will be of great hep to assess, analyse and plan future course of action for operating the patient under such low oxygen concentration present in the atmosphere. This will also be of great help to assess that upto what extent, moderate and extreme high altitudes have any role in the anaesthestic management of acclimatized individuals
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 17.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- Male
入选标准
- •Patients who are ASA I as per American Socitey of Anaesthesiology.
排除标准
- •Any patient below ASA I 2) History of Bronchial Asthma or any resp disease 3) History of smoking 4) Stay at these altitude of less than 6 weeks 5) History of Diabetes Mellitu and Hypertension.
结局指标
主要结局
Compare the opening SpO2 and then SpO2, HR before and after 6 minute walk test
时间窗: Compare the Breath Holding Time after adequate rest
次要结局
- Comparison of the above mentioned parameters and divide the individuals for pulse oximetry into less than 88, 88 to 92 and more than 92percent. As far as breath holding is concerned, will divide the individual on the basis of increase in heart rate as increase more than 15 percent, between 10-15 percent and less than 10 percent(For breath holding time , group will be divided as less than 25 sec, 15-25 sec and less than 10 sec)