Mitochondrial Capacity and Acylation in Young and Elderly Males - MCAGE

Wageningen Universiteit0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•* Male, 19-25 years
•* BMI 18.5-27 kg/m2
•* Normal activity levels: 1-2 times per week engaged in a structured exercise session ;Elderly
•* Male, 65-71 years
•* BMI 18.5-27 kg/m2
•* Normal activity levels: 1-2 times per week engaged in a structured exercise session
•* Short physical performance battery score >6

•* (known symptoms of) Metabolic diseases, e.g. type I or II diabetes,
•* Health concerns regarding respiratory and pulmonary diseases, e.g. COPD, (exercise induced) asthma and cardiovascular disease.
•* Impaired physical performance (defined as short physical performance battery score < 6) (only for elderly)
•* Contraindications for electrical stimulation, e.g. cardiac pacemaker
•* Contraindications for muscle biopsy, e.g. usage of anticoagulants (low dose aspirin allowed)
•* Regular smoker (defined as smoking >5 cigarettes per week)
•* Vastus lateralis skinfold > 30mm (due to tissue penetration depth of near-infrared light)
•* Haemoglobin concentrations below 8.0 mmol/L
•* Usage of recreational drugs, e.g. marihuana, amphetamines and cocaine during the study (starting after first screening day)
•* Recent usage (within four months) of supplements with suggestive training effects, e.g. creatine phosphate, EPO or anabolic steroids.
•* Current or recent (< 2 weeks) participation in other clinical trials
•* Employed or undertaking a thesis or internship at the department of Human and Animal Physiology

发起方