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临床试验/NCT02199977
NCT02199977已完成不适用

Innovative Public-private Partnership to Target Subsidized Antimalarials in the Retail Sector

Duke University1 个研究点 分布在 1 个国家目标入组 444 人开始时间: 2014年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
444
试验地点
1
主要终点
Effect of conditional drug subsidy on proportion of participants who choose to receive a free malaria diagnostic test

研究概览

简要总结

There are compelling medical and public health reasons to reduce unnecessary consumption of antimalarials and strong evidence to support the use of RDTs in malaria case management. The primary study hypothesis to be tested is that clients who know they will receive a subsidy conditional on a positive test are more likely to opt for testing before deciding which drug to buy. The primary endpoint is whether subjects choose to be tested for malaria with a rapid diagnostic test. The secondary endpoint is whether they purchased an artemisinin combination therapy (ACT) or not. The primary outcome of interest is to compare the proportion of participants who choose to receive a free malaria diagnostic test when they can receive a subsidy for a discounted drug conditional on a positive test (Group A compared to Group B) compared to those without the offer of a conditional subsidy. The investigators will use an experimental design that randomly assigns clients to one of four groups. Field workers will canvas households in the study area looking for individuals who have fever or history of fever or illness in the last 24 hours (current illness) who have not yet taken drugs or sought treatment outside the home. Clients who meet the inclusion criteria and give verbal consent to participate will be randomly assigned to one of the four groups. They will be given the location and contact information for their local community health worker who can provide a malaria rapid diagnostic test if they choose to be tested. They will also complete a survey tool. One week later, the field worker will return to interview the participant and determine whether they were tested, what action they took for their illness, what medicine they purchased and how much they paid. The investigators will summarize clients' choice by the four randomized study groups.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
1 Year 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Client is older than 1 year
  • Client has fever or history of fever or feeling unwell with a malaria-like illness within the last 24 hours
  • Client or their parent/legal guardian consents to participate

排除标准

  • Client has signs of severe disease or other problem requiring immediate referral to a community health worker (CHW) / health facility
  • Client has already sought treatment, purchased medicine or taken medicine for the current illness.
  • If more than one febrile person who meet the inclusion criteria are found in a single household, all of the individuals will be enrolled in the same group, but only one individual (the first enrolled) will be used for the purposes of the analysis.

结局指标

主要结局

Effect of conditional drug subsidy on proportion of participants who choose to receive a free malaria diagnostic test

时间窗: Within two days of group assignment

The primary outcome of interest is to compare the proportion of participants who choose to receive a free malaria diagnostic test when they can receive a subsidy for a discounted drug conditional on a positive test compared to those without the offer of a conditional subsidy.

次要结局

  • Effect of a conditional ACT subsidy on uptake of testing when the RDT is not free.(Within 2 days of group assignment)
  • Effect of malaria RDT subsidy on the uptake of testing (free versus paid RDT)(Within 2 days of group assignment)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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