Acute Effects of Endurance Exercise on Breastmilk Composition: Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Breastmilk metabolite composition
研究概览
简要总结
The investigators will determine the acute effect of exercise on breastmilk composition. Participants will come in to the lab on three different days, out of which they will exercise on two of these days and rest in the lab on the third day. The conditions will be randomly allocated to each participant. Breastmilk samples will be obtained in the morning of each test day, as well as immediately after, one hour after and four hours after the exercise/rest condition. Dietary intake will be standardized on the test days. At the time of study commencement, the trial (including planned analyses) is not fully funded. Additional milk will be stored for future analyses (not yet specified) when funding is secured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •6 to 12 weeks postpartum
- •Exclusive breastfeeding
- •Term birth
排除标准
- •Known cardiovascular disease
- •Type 1 or 2 diabetes mellitus
- •Limited ability to exercise
结局指标
主要结局
Breastmilk metabolite composition
时间窗: Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours)
Metabolomics profiling
次要结局
- Leptin(Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours))
- Cytokine profiling (Multiplex 27)(Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours))
- Insulin(Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours))
- Insulin Growth Factor-1(Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours))
- Adiponectin(Change from before exercise to after exercise (+0 hour, +1 hour, and + 4 hours))