Acute Effects of Endurance Exercise With Moderate and High Intensity on Breast Milk Composition Among Women With Overweight/Obesity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Breastmilk metabolite composition
研究概览
简要总结
The investigators will determine the acute effect of exercise on breastmilk composition. Participants will come in to the lab on three different days, out of which they will exercise on two of these days and rest in the lab on the third day. The conditions will be randomly allocated to each participant. Breastmilk samples will be obtained in the morning of each test day, as well as immediately after, one hour after and four hours after the exercise/rest condition. Dietary intake will be standardized on the test days.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Outcomes Assessor)
盲法说明
The personnel who will be analysing the milk samples will be blinded to which condition the samples were obtained from and the time-point.
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •6 weeks postpartum
- •Exclusively breastfeeding
- •Term birth
- •Singleton baby
排除标准
- •Known cardiovascular disease
- •Known type 1 or type 2 diabetes
- •Limited ability to exercise
结局指标
主要结局
Breastmilk metabolite composition
时间窗: Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours)
Global metabolomics profiling using MS/MS technology
次要结局
- Ghrelin(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Leptin(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Insulin Growth Factor-1(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Complex lipids composition(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Adiponectin(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Insulin(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))
- Cytokine profiling (Multiplex 27)(Change from before exercise to after exercise (+0 hour, +1 hour, and +4 hours))