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临床试验/NCT01745016
NCT01745016已完成不适用

The Effect of 28 Days of Beta-alanine Supplementation on the Physical Working Capacity at Heart Rate Threshold (PWCHRT)

University of North Carolina, Chapel Hill2 个研究点 分布在 1 个国家目标入组 35 人开始时间: 2013年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
35
试验地点
2
主要终点
Physical working capacity at heart rate threshold

研究概览

简要总结

Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.

详细描述

An equal number of men and women will be recruited [Men, n=20 (10 placebo [PL]; 10 beta-alanine (Active)]; [Women,n=20 (10 PL; 10 Active)]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Between the ages of 18-35 years old
  • Be recreationally active (defined as accumulating 1-5 hours of moderate intensity
  • Exclusion Criteria
  • Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire
  • Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months

排除标准

  • 未提供

结局指标

主要结局

Physical working capacity at heart rate threshold

时间窗: 0 to 4 weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Abbie Smith-Ryan, PhD

Assistant Professor

University of North Carolina, Chapel Hill

研究点 (2)

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