Relation betwEen abdominal aorta and carotid artery responses to SymPathetic stimulatiON uSing duplEx ultrasound - RESPONSE study

Rijnstate Ziekenhuis0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年4月15日

适应症

试验速览

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•- Young healthy group: Male or female between the age of 18 and 40 years
•- Older healthy group: Male or female, which are age-/sex-matched with the
•AAA patients group;
•- AAA patients group: Male or female with an abdominal aortic aneurysm who
•is still under surveillance, with a diameter between 3.0 and 5.0 cm and at
•least 18 years old. These patients may participate in the 1-2-3 Trial, which is
•a similar approved investigation by CMO region Arnhem-Nijmegen with
•registration number 2019-5216.
•- Informed consent form understood and signed;

•- Psychiatric or other conditions that may interfere with the study;
•- Participating in another clinical study, interfering on outcomes;
•- With regard to the necessary quality of the ultrasound images, BMI * 30
•- Increased risk for coronary spasms (score Rose-questionnaire * 2);
•- Presence of Raynaud*s phenomenon, Marfan syndrome, chronic pain
•syndrome at upper extremity(s), presence of an AV fistula or shunt, open wounds
•to the upper extremity(s), and/or scleroderma associated with placing the hand
•in ice water;
•- Recent (< 3 months) presence of angina pectoris, myocardial infarction,
•cerebral infarction, and/or heart failure, or PAD treatment.
•- Healthy groups:
•o Systolic blood pressure >140 mmHg and/or diastolic blood pressure >90 mmHg
•o Cardiovascular history
•o Antihypertensive medication

发起方

Rijnstate Ziekenhuis