The Impacts of the Different Anesthesia Methods on Patients of Transbronchial Cryobiopsy:A Prospective, Randomized, Controlled Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- the fluctuation of blood pressure
研究概览
简要总结
to evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy.
详细描述
To evaluate the difference between the tracheal intubation (TI) and rigid bronchoscopy (RB) under general anesthesia on patients with transbronchial cryobiopsy. Comparing the difference between two groups in the operating duration, extubation duration, total anesthesia time, heart rate, blood pressure and arterial blood gas analysis. This is a prospective, randomized, controlled trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The patients are admitted in the institution as ILD, while undefined after thorough history collection, laboratory examination and radiological data.
- •Transbronchial cryobiopsy(TBCB) is indicated by clinicians for definitive diagnosis and patients are content with the examination with agreement signed.
- •Blood gas analysis, routine blood test, ECG examination, coagulation function, immunological examination, chest HRCT, and liver/kidney function test have been completed
排除标准
- •The radiological data indicates non-ILD
- •The clinical examinations mentioned above are not completed.
- •The patient cannot endure or does not agree the procedure.
研究组 & 干预措施
trachial intubation
patient was insert trachial intubation with normal frequency jet ventilation
干预措施: anesthesia (Procedure)
rigid bronchoscopy
patient was insert trachial intubation with high frequency jet ventilation
干预措施: anesthesia (Procedure)
结局指标
主要结局
the fluctuation of blood pressure
时间窗: 24 hours
the fluctuation of blood pressure during the procedure
the fluctuation of heart rate
时间窗: 24 hours
fluctuation of heart rate during the procedure
the fluctuation of arterial partial pressure of carbon dioxide
时间窗: 24 hours
the fluctuation of arterial partial pressure of carbon dioxide during the procedure
次要结局
未报告次要终点
研究者
ShiYue Li
Director of the Respiratory department
Guangzhou Institute of Respiratory Disease