Effects of home-based and remotely supervised strength exercise programs combined with guideline-based aerobic physical activity modification on cognitive function in patients with Parkinson’s disease: a randomized, controlled, single-blinded trial

Inha University Hospital0 个研究点目标入组 64 人开始时间: 待定最近更新: 2023年12月19日

适应症

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•1) Patients who were diagnosed with Parkinson's disease based on the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria
•2) Patients who were aged between 50 and 80
•3) Patients with Hoehn and Yahr stage 3 or less
•4) Patients who did less than the recommended aerobic exercise proposed by the American College of Sports Medicine (ACSM) (ex.vigorous exercise done <75 minutes a week or moderate exercise done <150 minutes a week)
•5) Patients who were on stable dopaminergic pharmacotherapy over more than 3 months

•1) Patients with neurological, orthopedic, or cardiac comorbidities that make them unfit to do exercise
•2) Patients who were unable to complete questionnaires due to cognitive impairment (MoCA-K<18)
•3) Patients on antipsychotics
•4) Patients who have symptoms or signs suggesting atypical or secondary parkinsonism (ex. cerebellar signs, supranuclear gaze palsy, apraxia, prominent autonomic failure, or other cortical signs; multiple strokes with stepwise progression of symptoms)
•5) Patients who were unavailable for more than 10% of the study period

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