Investigating the effect of magnesium and thiamine combination to improve hyperglycemia and insulin resistance in type 2 diabetic patients

Esfahan University of Medical Sciences0 个研究点目标入组 100 人开始时间: 待定最近更新: 2023年11月13日

试验速览

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•Patients with a definitive diagnosis of type 2 diabetes for more than 5 years by a physician (plasma glucose level greater than 126 mg/dL and HbA1c between 6.5 and 8 percent at least 3 months before the start of the study)
•Men or women in the age range is over 18 years with a body mass index of 18.5 to 30 kg/m2 . 3
•Patients taking metformin
•Being able to communicate and volunteer to participate in the research.
•Signature written consent
•Residence in Isfahan city
•The possibility of continuous monitoring of patients.

•Pregnancy and breastfeeding
•Smoking and alcohol consumption during study and in the last year
•Suffering from other underlying diseases such as severe liver failure, kidney failure (serum creatinine more than 4 mg/dL), severe cardiovascular diseases, stroke up to 3 months before the start of the research, cancer, inflammatory diseases, severe infection, and thyroid disorders.
•Taking drugs such as insulin, immunosuppressive drugs, anti-inflammatories.
•Taking medicinal supplements containing magnesium, thiamine or a history of allergy to these drugs.
•Patients with severe ketosis.
•Change in the type or dose of diabetes medication during the intervention.
•Patients with poor and inappropriate nutrition and with persistent anemia (hemoglobin less than 6 mg/dL).
•Patients who consume less than 90% of the tested medication will be excluded from the study
•Traveling for more than two weeks

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