A randomised controlled trial of Ashwagandhadi Ghrita Nasya and Fluticasone Propionate nasal spray in the management of Vataj Pratishyaya (Allergic Rhinitis)
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- 1. Reduced Sneezing
研究概览
简要总结
Vataja Pratishyaya (Allergic Rhinitis) is common disease in day to day practice and contemporary science does not have proper solution for treating the same. Around 80% of the patient pool coming to Otorhinolaryngologist belongs to allergic rhinitis. Treatment according to modern science is avoidance of allergens, administration of nasal decongestants, corticosteroids and antihistamines, this may relieve symptoms but may lead to certain side effects. Recurrences are quite common even after treatment. Hence effective management of allergic rhinitis is necessary.
Nasya is the choice of treatment in Ayurveda for Vataja Pratishyaya. Ashwagandhadi Ghrita has ingredients which are found to have anti-inflammatory, analgesic, antioxidant, antihistaminic and antiallergic properties. The study is planned to develop evidence based support for Ashwagandhadi Ghrita nasya in the management of Vataja Pratishyaya .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Open Label
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient suffering from Kshawathu( sneezing), Nasa avarodha(nasal congestion), nasa kandu(nasal itching), nasa strava(nasal discharge), shiro gaurav(heaviness in head) and shwasa kashtata( difficulty in breathing).
排除标准
- •Pregnant and lactating women
- •Patients who need surgical and other intervention
- •Patients suffering from bacterial or viral rhinitis
- •Patients suffering from severe hypertension, malignancy, uncontrolled diabetes mellitus, heart disease and bronchial asthama.
结局指标
主要结局
1. Reduced Sneezing
时间窗: Enrollment: day 0 | Final follow-up: day 7
2. Improvement in breathing due to clearing of nasal passage.
时间窗: Enrollment: day 0 | Final follow-up: day 7
3. Reduced Nasal itching.
时间窗: Enrollment: day 0 | Final follow-up: day 7
4. Reduced Rhinorrhea
时间窗: Enrollment: day 0 | Final follow-up: day 7
5. Reduced frequency of Headache.
时间窗: Enrollment: day 0 | Final follow-up: day 7
次要结局
- Improvement in sleep quality(Enrollment: day 0)