Rumination: Mechanism of the antidepressant effect of exercise? Development of a decoder for the prediction of rumination during exercise

Eberhard Karls Universität Tübingen0 个研究点目标入组 6 人开始时间: 2020年8月6日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•informed, written consent;
•currently diagnosed moderate depression diagnosed with SKID-V (F32.1-F32.1, F33.1-F33.2);
•BDI-II Score > 20;
•Age between 18-40 years;
•fluent german skills;
•no psychopharmacological treatment;
•waiting period for ambulant psychotherapy > 2 months

•acute suicidality;
•schizophrenia and other psychotic disorders (F23, F20.81, F20.9 DSM-V);
•acute substance misuse except for tabacco (F10, F11, F12, F13, F14, F15, F16, F18, F19 DSM-V);
•current psychotherapy or start during the study period;
•current psychopharmacological treatment or start during study period;
•regular exercise (more then once a week for 30 minutes at a time endurance orientated exercise; e.g. jogging, cycling, swimming);
•acute or chronic diseases influencing brain metabolism:
•diabetes mellitus (E10-E14 ICD-10),
•kidney insufficiency from stadium 3 of the kidney disease outcome quality initative,
•non-adjusted hypertension (I10.x ICD-10), moderate to severe craniocerebral trauma (GSC 3-12) or rather craniocerebral trauma second or third degree with loss of concouisness for more than 30 minutes;
•medical contraindications for exercise:
•acute infectious diseases, medication intake, which in the opinion of the study physician do not permit an inclusion,
•allergic diseases in an acute episode,
•severe metabolic diseases,
•non-adjusted hypertension,
•cardiovascular diseases,
•orthopedic symptoms, which in the opinion of the study physician do not permit an inclusion

发起方