Mass Screening of the Population of the North Kynouria Municipality in Arcadia, Greece for the Detection of Cardiovascular and Stroke Risk Factors
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 7,000
- 试验地点
- 2
- 主要终点
- Emergency room visits
研究概览
简要总结
The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia, Peloponnese, Greece. The North Kynouria Study was initiated to assess modifiable and non-modifiable determinants of cerebrovascular and coronary heart disease.
详细描述
BACKGROUND:
The North Kynouria Project is a longitudinal, interventional-behavioural, prospective study aiming to identify cardiovascular/stroke risk factors, in the adult population of the municipality of North Kynouria, in the county of Arcadia, Peloponnese, Greece. The project, initiated in November 2022, recruits volunteers, of both sexes, over 18 years of age, irrespective of their personal history of cardiovascular disease. The epidemiology and burden of cardiovascular disease in North Kynouria remain unknown. The study aims to explore and document the prevalence of major cardiovascular/stroke risk factors, as well as the nutritional status, cigarette smoking, exercise habits, alcohol consumption, and overall quality of life of the inhabitants.
DESIGN NARRATIVE:
The screening exam is conducted at the Astros, Health Center, by obtaining the patient's personal history, and information about the patient's habits, such as physical activity, smoking, and alcohol consumption. Body weight, height, and waist-to-hip ratio are also measured. During the examination, blood pressure is evaluated using a pre-specified protocol, including assessment of orthostatic hypertension. Further testing includes electrocardiography, ankle-brachial index, direct ophthalmoscopy, and carotid and cardiac ultrasound. Blood samples are collected and stored at the deep freeze of the Astros premises, and blood count, lipid panel, and liver and kidney function are measured.
The main field of interest is the prevalence and burden of risk factors and cardiovascular disease in the wider region of North Kynouria, Arcadia Greece. The project aims to assess the epidemiology of CVD and consequently improve public health and engage with the local community through healthy behavioral education.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •residents of North Kynouria
排除标准
- •under 18,
- •pregnancy
结局指标
主要结局
Emergency room visits
时间窗: up to 5 years after enrollment
Any cause of emergency room visit
Major adverse cardiovascular events
时间窗: up to 5 years after enrollment
myocardial infarction, ischemic and hemorrhagic stroke
All-cause mortality
时间窗: up to 5 years after enrollment
Death by any cause, cardiovascular, infection, cancer, other
Hospitalizations
时间窗: up to 5 years after enrollment
Any cause hospitalization
次要结局
- New diagnosis of diabetes mellitus(up to 1 year after enrollment)
- New diagnosis of Arterial hypertension(up to 1 year after enrollment)
- New diagnosis of carotid atherosclerosis(up to 1 year after enrollment)
- New diagnosis of peripheral artery disease(up to 1 year after enrollment)
- New diagnosis of dyslipidemia(up to 1 year after enrollment)
研究者
Liontos Angelos
MD, MSc, PhD
University Hospital, Ioannina