NCT05948527已完成不适用
Safety and Efficacy of High Flow Nasal Canula in Patients With Mild Hypercapnia
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Arterial Blood Gases changes
研究概览
简要总结
Evaluate safety and efficacy of application ( high flow nasal canula) in cases with mild hypercapnia, included 30 patients who were hospitalized in Mansoura University chest department with mild Hypercapnia (Pco2 range 45-60 mmhg and power of hydrogen not less 7.30) of different pulmonary disease categories (Chronic obstructive pulmonary disease acute exacerbation, pneumonia, Interstitial lung diseases, etc).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with mild Hypercapnia
排除标准
- •Excluded cases had age less than 18 years or pediatric group .
- •patients with their mental state altered, confused, comatose, severe agitation or non cooperative
- •Cases with moderate or severe Hypercapnia
- •cases in need for immediate invasive mechanical ventilation
- •cases with respiratory rate more than 35 breath per minute.
- •cases with Respiratory exhaustion , fatigue , excess use of respiratory accessory muscles
- •Shock , hemodynamic instability, post arrest cases,
- •cases with facial trauma or severe nasal deformity,
- •Patients with sleep breathing disorders or upper airway obstruction
- •patients with history of home ventilation prior admission
结局指标
主要结局
Arterial Blood Gases changes
时间窗: 48 hours
The primary outcome was concerned about changes in Arterial Blood Gases in first 24 h after admission and the same changes 48 h after admission.
次要结局
- Number of participants in need for ventilation(7 days)
研究者
研究点 (2)
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