NCT04978948招募中不适用
Study of STIM1 Membrane Expression During Autoimmune Diseases
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 670
- 试验地点
- 8
- 主要终点
- level of STIM1-PM
研究概览
简要总结
The aim of this study is to determine the expression of STIM1 in the plasma membrane of lymphocytes from patients suffering from different autoimmune diseases in order to identify new pathologies of interest presenting an over-expression of STIM1PM.
This would allow to initiate, following this study, research and development programs on the use of anti-STIM1 antibodies in these identified autoimmune diseases of interest.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of one of the autoimmune diseases
排除标准
- •Treatment with rituximab in the previous 12 months
结局指标
主要结局
level of STIM1-PM
时间窗: Day 0
Membrane expression level of STIM1-PM on the surface of immune cells, measured by flow cytometry
次要结局
- correlation between STIM1 expression and Clinical Score(Day 0)
研究者
研究点 (8)
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