ISRCTN11319909已完成2 期
Examining the role of Early Neoadjuvant and Synchronous Erbitux in Preoperative Chemo-Radiotherapy using Xeloda followed by Excisional Surgery
niversity College London (UK)0 个研究点目标入组 22 人开始时间: 2010年5月12日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 22
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adenocarcinoma of the rectum (within 15 cm of anal verge)
- •2. Tumour tissue available for testing of epidermal growth factor receptor (EGFR) status
- •3. Indication for pre-operative chemoradiotherapy with R0 resection unlikely
- •4. Fit for chemotherapy
- •5. Written informed consent for both treatment and biopsies
- •6. Male and female, lower age limit of 18 years
排除标准
- •1. Previous radiotherapy to the pelvis
- •2. Previous pelvic resectional surgery (cystectomy, hysterectomy)
- •3. Previous chemotherapy or radiation for rectal cancer
- •4. Previous chemotherapy for metastatic disease
- •5. Patients who have very significant small bowel delineated within the radiation fields
- •6. Currently enrolled in any other treatment trial
研究者
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