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临床试验/NCT02459782
NCT02459782已完成不适用

Ultrasound Guided Peribulbar Anaesthesia: a Real-time Ultrasound Guided Technique With a Novel Dual Quadrant Injection

Sunnybrook Health Sciences Centre0 个研究点目标入组 22 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
22
主要终点
Block Success

研究概览

简要总结

Peribulbar anaesthesia for ocular surgery depends on the spread of local anaesthetic throught the orbit to be successful and has a relatively high failure rate. This study will examine a novel ultrasound guided approach to peribulbar anaesthesia which should extend the depostion of local anaesthetic by using a dual quadrant injection technique. The study will assess the feasibility of this technique, how successful it is and whether any obvious safety issues arise with its use.

详细描述

Peribulbar anesthesia is widely used for anterior and posterior chamber ophthalmic procedures. It is a blind technique which is traditionally carried out by inserting a needle in the infero-lateral aspect of the orbit below the globe and injecting a volume of 8 - 12 mL of local anesthetic in the periorbital space. The goal of this inejction is to achieve akinesia and anesthesia of the eye sufficient for surgery. The technique has a relatively high failure rate of up to 30%. A failure or insufficient block requires a second or rarely a third peribulbar injection to achieve success. Ultrasound can be used to guide needles in the human body and has been successfully used in many anatomic locations for anaesthesia. This study will assess whether ultrasound can guide the block needle in ophthalmic anesthesia to deliver local anesthetic via a single entry into two discrete locations within the periorbital space - the first in the infero-lateral quadrant and the second in the infero-medial quadrant. If this can be done the investigators may achieve a higher success rate for this block with a lower volume potentially improving the quality of the block and its safety.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
盲法
None

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ASA score less than III and ability to provide a written informed consent
  • 22 patients presenting for opthalmic surgery

排除标准

  • Coagulation disorder or anticoagulated with INR > 1.5
  • Platelet count < 75 X 10*9/L
  • Significant Myopia (axial length > 28mm)
  • Patients unable to lie supine for 2 hours
  • Patients with recent gas or silicone injections in/around the eye

结局指标

主要结局

Block Success

时间窗: 10 minutes post intervention

Block will be deemed a failure if a supplementary block is required for the operative procedure

次要结局

  • Block Quality (standardized Ocular Scoring System for akinesia and anaesthesia)(5 and 10 minutes)
  • Duration of Procedure(1 to 10 minutes)
  • Complications(6 Weeks)
  • Image Visualization(1 minute)
  • Block Volume(1 minute)

研究者

申办方类型
Other
责任方
Sponsor

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