NCT06330155尚未招募不适用
A Genetic Study for Alzheimer Dementia: Case-control Study
MinYoung Kim, MD, PhD0 个研究点目标入组 20 人开始时间: 2024年3月26日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 主要终点
- genetic analysis
研究概览
简要总结
The purpose of this study is to find out the difference in genetic test results between Alzheimer's dementia patients and healthy subjects.
The investigators want to identify genes that are importantly related to Alzheimer's dementia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Alzheimer's dementia patient
- •Adult patients over 60 years old
- •Patients with a Alzheimer's dementia patient
- •Total Korean version of mini-mental state examination (K-MMSE) score less than 24
- •Total Clinical Dementia Rating (CDR) over 0.5
- •Inclusion Criteria: healthy subjects
- •Adult healthy over 60 years old
- •Total Korean version of mini-mental state examination (K-MMSE) over 24
- •Total Clinical Dementia Rating (CDR) is 0
排除标准
- •Those with severe medical conditions such as unstable conditions of the cardiovascular system, digestive system, respiratory system, endocrine system, etc., who are in poor general condition
- •In the case of a person with impaired consent (MMSE less than 10 points), if not accompanied by a guardian
- •Other cases where the researcher determines that participation in this clinical trial is not appropriate (Patients who are participating in other studies or have participated in other studies within the past 30 days can also participate in this study.)
结局指标
主要结局
genetic analysis
时间窗: Baseline
5cc blood collection for genetic testing
次要结局
- Measurement of Korean version of mini-mental state examination (K-MMSE)(screening, Baseline)
- Measurement of Geriatric Depression Scale (GDSd)(Baseline)
- Measurement of Clinical Dementia Rating (CDR)(screening, Baseline)
研究者
MinYoung Kim, MD, PhD
Sponsor-Investigator
Bundang CHA Hospital
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