Randomized Control trial of Continuous positive airway pressure versus Standard care in neonates with moderate meconium aspiration syndrome in reducing the need for invasive ventilation

Meconium aspiration syndrome is one of the commonest cause of morbidity in term neonates. Neonates with moderate MAS will be randomized either into CPAP  or standard group after taking written consent from parents. In CPAP group, enrolled neonate will be kept on continuous positive airway pressure (CPAP) according to protocol while in standard group, neonate will be kept on oxygen by hood/ ventilator depending on the respiratory status. They will be monitored for the clinical outcomes till discharge/death. All the neonates will be managed according to standard protocols for the hemodynamic stability and other problems.