Procalcitonin and C-Reactive Protein as Early Anastomotic Dehiscence Markers in Ovarian Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 92
- 试验地点
- 1
- 主要终点
- Number of patients with anastomotic leak detected by elevation of C-reactive protein and procalcitonin levels
研究概览
简要总结
EDMOCS trial pretends to evaluate if C-reactive protein (CRP) and procalcitonin (PCT) can predict intestinal anastomotic leaks before early discharge in advanced ovarian cancer surgery requiring intestinal resection. These markers have already been positively tested in colorectal cancer surgery, but not yet in ovarian surgery.
Patients undergoing intestinal resection in ovarian cancer surgery will be included. C-reactive protein and PCT will be measured pre-operatively, and on the second, fourth and sixth postoperative day. Thirty-day readmissions, re-operations and mortality will be recorded.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Ovarian cancer stage III-IV
- •Intestinal resection needed
排除标准
- •Infection diagnosed at time of surgery.
- •Urgent surgery
结局指标
主要结局
Number of patients with anastomotic leak detected by elevation of C-reactive protein and procalcitonin levels
时间窗: Within the first 30 days after the surgery
To evaluate whether C-reactive protein (CRP) and procalcitonin (PCT) can predict anastomotic leak before early discharge.
次要结局
- C-reactive protein and procalcitonin measures in patients without complications in ovarian surgery.(Within the first six days after the surgery)