Comparison of effects of Dexmedetomidine and Midazolam in attenuating fragmented sleep related glycemic variability in post operative intensive care patients - a single blinded placebo controlled prospective randomized study

Calcutta national medical college hospital0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年10月17日

试验速览

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•1.Patient and their relatives who consented for the study
•2.Adults of the age 18-55 years of age
•3.Patients who got admitted in SICU, MICU following post-operative emergency surgeries.
•4.Patient who received Non-invasive ventilation in form of Cpap and BiPap with better prognosis.
•5.Patients who were studied within 72 hours of surgery performed.

•1.Patients refused to give consent
•2.Known prior diabetic history, or under Oral hypoglycemics or Insulin during or before hospital stay.
•3.Paediatric patients ( <18 years)
•4.Patients with allergy to study drugs
•5.Liver dysfunction or confirmed renal impairment (CKD, DCLD)
•6.Patients who had known neurological (Epilepsy, Guillian Barre syndrome etc) or endocrinological (cushings disease, addisons disease etc.) disorders prior to the study.
•7.Patients who were diagnosed with sepsis according to the recent SIRS guidelines.
•8.Pregnant patients and lactating mothers
•9.Patients who were on opioids like tramadol, fentanyl infusion during the study period.
•10.Known prior cardiac illness like A-V block, previous MI, pacemaker implantation.
•11.Patient who are ventilated and have poor prognosis.
•12.Patients who are on additional muscle relaxant infusion
•13.Patients who require vasopressor like Noradrenaline or dopamine infusions to maintain Mean arterial pressure above 65 mm Hg
•14.Patients admitted for severe burns or road traffic accidents
•15.Patients with BMI >30 and severely obese patients

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