NL-OMON31934已完成不适用
Mannitol inhalations as a new procedure for testing of airways hyperresponsiveness - Mannitol en AHR
ongziekten0 个研究点目标入组 120 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Asthmatics:
- •- Episodic symptoms of dyspnea, and/or wheezing, and/or cough
- •- Allergic or non-allergic
- •- non current smokers (> 0.5 years)
- •- PC20 MCh < 8 mg/ml;COPD patients:
- •- Age > 40 yrs
- •- Active or former smokers, with a smoking history of more than 10 packyears
- •- Continuous symptoms of cough/sputum and/or dyspnea on exertion
- •- No history of asthma
- •- FEV1/FVC < 70 % and FEV1 between 50 and 80 % pred.;Controls
- •- No history of asthma or COPD
- •- PC20 MCh > 8 mg/ml
- •- FEV1/FVC > 70 % and FEV1 > 90 %pred.
排除标准
- •m- Age < 18 years
- •- Inability to perform acceptable-quality spirometry or to understand directions given by personnel
- •- Severe airflow limitation (FEV1 < 50% of predicted or < 1.0 L)
- •- Heart attack or stroke in last 6 months
- •- Uncontrolled hypertension, systolic BP > 200, or diastolic BP > 100
- •- Known aortic aneurysm
- •- Pregnancy
- •- Nursing mothers
- •- Current use of cholinesterase inhibitor medication (for myasthenia gravis)
研究者
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Mannitol inhalations as faster procedure for testing of airways hyperresponsiveness.NL-OMON21125Department of Respiratory MedicineUniversity Medical Center GroningenPostbox 30.0019700RB Groningenthe Netherlands120
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