The Acute Effect of Egg-Based High Protein Meal on Hypertensive Response to Exercise
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Blood Pressure Changes
研究概览
简要总结
The primary purpose of this study is to explore the effect of high versus normal egg-based protein meals on acute exercise-induced elevated blood pressure.
详细描述
This study is designed to assess BP changes during and post- exercise after consumption of a test breakfast. The design consists of three visits. The first visit will assess each participants aerobic exercise capacity (VO2 max). Visit 2 and 3 will be clinical testing days where the subject will consume either the 13g or 30g protein breakfast in a randomized cross-over manner and perform the exercise intervention. BP changes will be monitored before and after breakfast consumption, during the exercise intervention,
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
盲法说明
Care provider will randomize participants and keep the participant, investigator and outcomes assessor blinded to the randomization.
入排标准
- 年龄范围
- 21 Years 至 121 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Pre-hypertensive (systolic, 120-139 mm Hg; diastolic, 80-89 mm Hg
- •Body weight <300 lb (136 kg)
- •BMI between 20 and 34.9 kg/m2
- •Fasting plasma glucose <6.1 mmol/L,
- •total cholesterol <6.7 mmol/L
- •LDL cholesterol <4.1 mmol/L
- •TG <4.5 mmol/L
- •No pre-existing or history of cardiovascular, renal or liver disease
- •Not currently or previously (past 6 mo) consuming a weight-loss diet or other special/non-balanced diets
- •No weight loss/gain (±4.5 kg) within the past 6 mo
- •No physical impairments preventing properly exercise execution
- •No caffeine intake the day of testing
排除标准
- •Hypertensive
- •Body weight ≥ 300 lb
- •BMI <20 or >35 kg/m2
- •Pregnant or planning pregnancy
- •Unwilling to consume study foods and beverages
- •Fasting plasma glucose ≥6.1 mmol/L
- •Total cholesterol ≥6.7 mmol/L
- •LDL cholesterol ≥4.1 mmol/L
- •TG ≥4.5 mmol/L
- •acute illness
- •pre-existing or history of cardiovascular, renal or liver disease
- •currently or previously (past 6 mo) consuming a weight-loss diet or other special/non-balanced diets
- •weight loss/gain (±4.5 kg) within the past 6 months
- •physical impairments preventing properly exercise execution
- •caffeine the day of testing
研究组 & 干预措施
High Protein
Consumption of high protein (HP) meal
干预措施: HIgh Protein (Other)
Normal Protein
Consumption of normal protein (NP) meal
干预措施: Normal Protein (Other)
Normal Protein
Consumption of normal protein (NP) meal
干预措施: HIgh Protein (Other)
High Protein
Consumption of high protein (HP) meal
干预措施: Normal Protein (Other)
结局指标
主要结局
Blood Pressure Changes
时间窗: 6hr testing
Changes from Baseline to Post Systolic Blood Pressure during 30 minute exercise session
次要结局
- Vasoactive Molecules(6 hrs)
研究者
Wayne Campbell
Principal Investigator
Purdue University