NCT01636869已完成4 期
Plasma Concentrations of Bupivacaine After Spinal Anesthesia With Single Shot Femoral Nerve Block and Peri-articular Injection in Total Knee Arthroplasty
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 43
- 试验地点
- 1
- 主要终点
- plasma concentration of bupivacaine after spinal anesthesia with single-shot femoral nerve block and periarticular block
研究概览
简要总结
Patients with knee arthroplasty usually performed under spinal anesthesia with a single-shot femoral nerve block and periarticular block, so we would like to know the plasma concentration of bupivacaine in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age of 30-70 yr
- •patient undergo total knee arthroplasty under spinal block and single shot femoral nerve block and periarticular block
排除标准
- •patient's refusal
- •allergic to bupivacaine
- •body weight less than 50 kg
- •liver disease
- •heart disease
- •coagulopathy
- •infection at both groin
研究组 & 干预措施
bupicavaine
Experimental
干预措施: Bupivacaine (Drug)
结局指标
主要结局
plasma concentration of bupivacaine after spinal anesthesia with single-shot femoral nerve block and periarticular block
时间窗: 2 hours
次要结局
- bupivacaine toxicity(24 hr)
研究者
Saowaphak Lapmahapaisan
instructor
Mahidol University
研究点 (1)
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