NCT05398822已完成不适用
The Role of TextRAd on Detection of Liver Metastasis in Rectal Cancer
East Suffolk and North Essex NHS Foundation Trust1 个研究点 分布在 1 个国家目标入组 113 人开始时间: 2019年7月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 113
- 试验地点
- 1
- 主要终点
- Local recurrence of rectal cancer
研究概览
简要总结
This is a retrospective analysis of all patients diagnosed with LARC who received NCRT and had MRI scans between 2003-2014 at East Suffolk and North Essex NHS Foundation Trust. Region of interest was drawn around the tumor or its location on T2 MRI images. Six texture parameters were systematically extracted from Textural histograms of post-treatment scans. These parameters were examined to determine their ability to predict local recurrence and distant metastases through Kaplan-Meier survival curves and log-rank tests.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All subjects must have MRI post-Chemotherapy treatment to detect the response to Neoadjuvant treatment and compare it to pre-treatment scans to easily determine if there were a posttreatment liver metastasis.
- •Locally advanced rectal cancer (LARC) = MRI stage: T3/T4 and/or N1/N0.
排除标准
- •Distant metastases.
- •Synchronous tumour.
结局指标
主要结局
Local recurrence of rectal cancer
时间窗: 120 months
次要结局
未报告次要终点
研究者
研究点 (1)
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