NCT00726817已完成不适用
The Effects of Butyrate Enemas on Visceral Perception
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 1
研究概览
简要总结
During this double blind, placebo controlled, randomised cross over study, healthy volunteers received an enema once daily for one week containing either placebo (saline), 50mM butyrate or 100mM of butyrate. Before and directly after each test period a barostat protocol was performed to measure parameters for visceral perception.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •age, under 18 or over 65
- •use of pre- or probiotics during study and 3 months previous to study
- •previous bowel complaints
- •gastrointestinal disease or abdominal surgery
研究组 & 干预措施
1
Placebo Comparator
enemas, once daily, containing saline
干预措施: Butyrate (Drug)
2
Experimental
enemas, once daily, containing 50mM butyrate
干预措施: Butyrate (Drug)
3
Experimental
enemas, once daily, containing 100mM butyrate
干预措施: Butyrate (Drug)
研究者
研究点 (1)
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