Cognitive Bias Modification for Paranoia: a randomised controlled trial

Guy's Campus, King's College London0 个研究点目标入组 62 人开始时间: 2016年5月12日最近更新: 2024年7月22日

适应症

试验速览

2017 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/28662715 protocol 2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31337373 qualitative results (added 25/07/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/32779945/ results (added 13/08/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33973108/ questionnaire evaluation results (added 12/05/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35699135/ feasibility, effects, dose-response and primary outcomes for future trials (added 10/07/2024)

•1. Any diagnosis featuring clinically significant persecutory or paranoid symptoms, present for at least the preceding month
•2. Above threshold (>2 on item 6) on the paranoia item of the Positive and Negative Symptoms Scale
•3. Displaying a baseline interpretation bias, as measured by the 'Scrambled Sentences Task'
•4. Stable on medication for at least the last 3 mths and expected to be so for study duration
•5. Age 18-65
•6. Capacity to consent

•1. Severe cognitive impairment
•2. Illiteracy
•3. Major physical illness (cancer, heart disease, stroke)
•4. Major substance or alcohol misuse
•5. Currently receiving, or soon due to receive, a psychological intervention targeting the same psychological mechanisms as CBM-pa (paranoid beliefs), or having done so in the last 3 months

发起方

Guy's Campus, King's College London