Regulation of Intracerebral Pressure During Electroconvulsive Therapy. Does Systemic Bloodpressure Reflect the Intracranial Pressure?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Pulsatility Index before, during and after electroconvulsive therapy
研究概览
简要总结
The purpose of this study is to determine whether electroconvulsive therapy (ECT) has an influence on pressure within the human brain before, during and after ECT.
详细描述
-
Aim:
-
Our main objective concerning this study is to determine to what extent ECT does lead to an increase of the Pulsatility Index (as an indicator of intracerebral pressure) measured by a Transcranial Doppler Device (TCD).
-
As a secondary objective we want to compare the PI measurements with simultaneously measured systemic blood pressure.
-
Study design:
a.Observational study: cohort study 3. Treatment:
a. Treatment as usual, PI and blood pressure measurement at baseline, just before ECT, during and 5 minutes after ECT. Data will be collected during unilateral treatment during 3 consecutive ECT treatments. 4. Endpoints:
- A minimum of sixteen patients are needed according to the power analysis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Temporal window to measure PI
- •Major depression
- •Psychotic depression
排除标准
- •Under 18 years of age
结局指标
主要结局
Pulsatility Index before, during and after electroconvulsive therapy
时间窗: before, during and after three consecutive ECT treatments
次要结局
- Bloodpressure before, during and after ECT.(before, during and after three consecutive ECT treatments.)