NL-OMON56753尚未招募不适用
uminal Fructose Kinetics - MARTINI
Amsterdam UMC0 个研究点目标入组 22 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 22
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 64（—）
入选标准
- •In order to be eligible to participate in this study, a subject must meet all
- •of the following criteria:
- •In case of the healthy subject group:
- •- Adult individuals, age > 18 <65 years
- •- male / postmenopausal female
- •- BMI <25
- •- Ability to give informed consent
- •In case of the MASLD/MASH group
- •- Adult individuals, age > 18 <65 years
- •- BMI > 25
- •- male / postmenopausal female
- •- Biopsy proven MASLD/MASH
- •- Ability to give informed consent
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:
- •- History of sustained excess alcohol ingestion: daily consumption >30g/day (3
- •drinks per day) for males and >20 g/day (2 drinks per day) for females
- •- Patients with diabetes
- •- Bariatric surgery
- •- Other forms of liver disease (e.g. Hepatitis B,C, Wilson disease,
- •hemochromatosis)
- •- Proton-pump inhibitor usage one year prior to study participation
- •- GLP1, SGLT2i or insulin use
- •- Antibiotic use for the past 3 months
- •- Probiotic or symbiotic usage
- •- Pregnant women
- •- Chronic illness (including a known history of heart failure, renal failure
- •(eGFR <30 ml/min), pulmonary disease, gastrointestinal disorders, or
- •hematologic diseases), or other inflammatory diseases
- •- Active infection
- •- Use of ascal, clopidogrel or other platelet inhibition
- •- Blood thinners
- •- Heart failure
研究者
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