ISRCTN16168569已完成未知
Multicentre RCT to determine the clinical and cost effectiveness of septoplasty compared with non-surgical strategy in the management of nasal septal deviation in adult patients with nasal airway obstruction in the presence of a deviated nasal septum, what is effectiveness of septal surgery with turbinate reduction compared with 6 months’ topical nasal treatment in improving nasal symptoms
ewcastle Upon Tyne NHS Foundation Trust0 个研究点目标入组 378 人开始时间: 2017年3月24日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 378
研究概览
简要总结
2020 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/32054508 protocol (added 17/02/2020) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37852641/ (added 19/10/2023) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38477237/ (added 13/03/2024)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Adults aged =18 years with a baseline NOSE score =30
- •2. Septal Deflection visible at naseondoscopy
- •3. Capacity to provide informed written consent and complete the study questionnaires.
排除标准
- •1. Patients <18 years
- •2. Patients with a baseline NOSE score <30
- •3. Any prior septal surgery
- •4. Systemic inflammatory disease
- •5. Granulomatosis with poly angiitis
- •6. Naseondoscopic evidence of unrelated associated pathology eg. adenoid pad, septal perforation, chronic rhinosinusitis indicated by the prescence of polyposis or pus
- •7. Intranasal recreational drug use
- •8. Breastfeeding, pregnancy or intended pregnancy
- •9. Bleeding diathesis
- •10. Therapeutic anticoagulation
- •11. Known adverse reactions to general anaesthesia
- •12. Immunocompromised patients
研究者
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