KCT0006904招募中未知
Comparison of requirements for deep neuromuscular block effect during continuous and intermittent bolus injection of rocuronium in patients under general anesthesia: a randomized equivalence trial
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 18?(Year) 至 65?(Year)（—）
- 性别
- All
入选标准
- •1) Patients aged 18-65 years
- •2) Patients undergoing general anesthesia for elective abdominal (gastrointestinal tract, colon and rectal, liver) surgery
- •3) Patients whose operation time is expected to be more than 2 hours
- •3) Patients corresponding to American Society of Anesthesiologist Status 1-2
排除标准
- •1) Patients under total venous anesthesia
- •2) Emergency surgery patients
- •3) body mass index = 30 kg/m2
- •4) Pregnant and lactating women
- •5) Patients with lung diseases such as asthma and COPD
- •6) Patients with a history of treatment for cerebrovascular disease
- •7) Patients allergic to drugs (including neuromuscular blocking agent):
- •- Patients with a history of hypersensitivity to sevoflurane, desflurane, or other halogenated anesthetics.
- •- Patients with a history of hypersensitivity to remifentanil and other fentanyl analogues all.
- •- Patients with a history of hypersensitivity to rocuronium and any of its components or neuromuscular blockers
- •8) Patients with kidney disease (patients with creatinine clearance less than 60ml/min, patients with renal impairment with a baseline blood creatinine value of 1.5 mg/dL or more)
- •9) Patients with liver dysfunction
- •10) Patients with neuromuscular junction disease, including patients with myasthenia gravis and myasthenia gravis
- •10) Patients who have difficulty in voluntary consent;
- •11) Patients with a history of psychiatric disorders, including those with difficulty in normal communication
- •12) Past and family history of malignant hyperthermia or allergy to drugs administered during general anesthesia, and taking drugs known to interact with rocuronium during surgery (some antibiotics, metronidazole, also phenytoin and carbamazepine, diuretics, monoamine oxidase inhibitors, calcium channel blockers, corticosteroids, and those containing magnesium ions).
- •13) Patients with a history of difficult endotracheal intubation
研究者
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