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临床试验/CTRI/2024/05/067543
CTRI/2024/05/067543尚未招募不适用

A Prospective observational study to analyse the treatment response, tolerability and prescribing pattern in patients receiving treatment for Recalcitrant Dermatophytosis

Priti kochar1 个研究点 分布在 1 个国家目标入组 347 人开始时间: 2024年5月22日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
347
试验地点
1
主要终点
To analyse the treatment response to antifungals drugs in patients diagnosed with recalcitrant dermatophytosis patients.

研究概览

简要总结

Recalcitrant dermatophytosis refers to the relapse, recurrence, reinfection, persistence, and possibly microbiological resistance of dermatophytosis. In the last 6-7 years dermatologists have seen an increase in chronic and recurrent dermatophytosis. Superficial fungal infections account for nearly 25%of global skin mycoses making these infections one of the most common types of infectious diseases worldwide. The rising epidemic of recalcitrant dermatophytosis is also adversely impacting the physical, mental, and financial health of the patients..A wide variety of antifungals are available for the treatment of recalcitrant dermatophytosis. While patients often experience symptomatic relief through pharmacological management in recalcitrant dermatophytosis, their responses to drugs vary significantly. There is a lack of clear-cut guidelines and efficacy for preferred antifungal agents. The duration of the treatment is also not well defined. This disease is also affecting the quality of life of the patients. Therefore, the present study is designed to assess the treatment response to prescribed drug therapy and analyze the prescribing pattern in recalcitrant dermatophytosis patients.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • All the patients diagnosed with recalcitrant dermatophytosis operational definition of Recalcitrant dermatophytosis refers to relapse, recurrences, reinfection, persistence or chronic infections, and possibly microbiological resistance.
  • Both male and female with established recalcitrant dermatophytosis.
  • Age 18- 60 years.

排除标准

  • 1.Patient diagnosed with other autoimmune dermatological disease like psoriasis.
  • Patient with cutaneous adverse drug reactions.
  • Patient with secondary infected tinea infection.

结局指标

主要结局

To analyse the treatment response to antifungals drugs in patients diagnosed with recalcitrant dermatophytosis patients.

时间窗: At baseline and four weeks

次要结局

  • 1. To assess the prescribing pattern of anti-fungal agents and adherence(to available treatment guidelines.)

研究者

发起方
Priti kochar
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Priti Kochar

AIIMS Rishikesh

研究点 (1)

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